Biochemistry Research Associate

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Biomedical Systems / Biology
💼
REDD - Research & Exploratory Development Department

Do you marvel at the complexity of biology and seek to develop new applications based on novel protein chemistries? 

 

Would you like to contribute your protein biochemistry expertise to an interdisciplinary team of scientists, focused on application development for national security? 

 

If you answered yes to these questions, we're looking for someone like you to join our team, in the Biological Sciences Group, here at the Johns Hopkins University Applied Physics Lab. 

 

We are seeking a Biochemistry Research Associate to assist in development of protein-based biotechnologies. You should have some combination of skills in protein purification, isolation of biochemical compounds from complex samples, and biochemical assays. Experience with design of enzyme inhibitors and biophysical characterization of proteins including structural or computational studies is a major plus. As part of the Biological Sciences Group in the Research Exploratory Development Department, this position is at the forefront of APL's mission to provide impactful contributions to critical challenges. A highly motivated Biochemist will contribute to building extraordinary expertise in pursuit of challenges in areas of defense and national health. 

 

As a Biochemistry Research Associate you will...

  • Drive experimental execution focused to develop novel protein inhibitors.

 

  • Support study design, execution, and data analysis. 

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  • Assist and collaborate with scientists in support of laboratory-based experimentation.

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  • Troubleshoot and optimize experimental protocols.

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  • Assist with basic laboratory functions (i.e. lab cleanliness and organization, equipment upkeep, etc.).

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  • Communicate key findings both internally across teams and externally to sponsors.

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  • Participate in the biology and APL community, and present data at lab meetings and to department management. 

 

You meet our minimum qualifications for the job if you ...

 

  • Have B.S. in Biochemistry, Molecular Biology, Microbiology, or a similar field with 1+ years of experience in a laboratory setting.

 

  • Have experience designing, running, and troubleshooting a wide range of biological assays.

 

  • Have extensive experience with recombinant protein expression, protein purification and characterization.

 

  • Have demonstrated expertise with culture and genetic manipulation of bacteria and yeast to produce recombinant products.

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  • Are able to obtain a Secret level security clearance. If selected, you will be subject to a government security clearance investigation and must meet the requirements for access to classified information. Eligibility requirements include U.S. citizenship.​​​​​​​

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  • Can demonstrate that you are fully vaccinated against COVID-19. To ensure the safety and well-being of the community, APL has established a policy requiring that all staff be vaccinated against COVID-19. All staff members must provide proof of full vaccination or have an approved medical or religious accommodation by their start date.

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You'll go above and beyond our minimum requirements if you ...

 

  • Are well-versed in molecular biology techniques, including design and construction of genetic constructs.

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  • Have experience working with enzymes with complex cofactors like metal cofactors especially p450s or other aspects of bioinorganic chemistry.

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  • Have expertise developing enzyme assays that require the use of HPLCs.

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  • Have demonstrated expertise developing enzyme inhibitors.

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  • Have experience working with enzymes involved in plant secondary metabolism.

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  • Have demonstrated proficiency in fluorescence and confocal imaging, including image analysis with Image J or Matlab and immunocytochemistry or immunofluorescence.

 

Why work at APL?

 

The Johns Hopkins University Applied Physics Laboratory (APL) brings world-class expertise to our nation’s most critical defense, security, space and science challenges. While we are dedicated to solving complex challenges and pioneering new technologies, what makes us truly outstanding is our culture. We offer a vibrant, welcoming atmosphere where you can bring your authentic self to work, continue to grow, and build strong connections with inspiring teammates. 

 

At APL, we celebrate our differences and encourage creativity and bold, new ideas. Our employees enjoy generous benefits, including a robust education assistance program, unparalleled retirement contributions, and a healthy work/life balance. APL’s campus is located in the Baltimore-Washington metro area. Learn more about our career opportunities at www.jhuapl.edu/careers.

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