Biomedical Systems / Biology
REDD - Research & Exploratory Development Department

Are you interested in finding new ways to use biology to solve today’s National Security and National Health challenges?


Are you passionate about using your knowledge of computational biology to enable new capabilities?


Do you thrive in a diverse, fast-paced and highly-collaborative scientific environment?


If so, we're looking for someone like you to join our team at APL!


We are seeking a Computational Biologist to support operational genomics research. As part of the Research & Exploratory Development Department, our group conducts basic and applied research to characterize pathogen evolution and understand complex biological communities. We work to develop advanced genome sequencing and analytical approaches to support rapid data sharing, decision making, and understand variability in natural populations over time. In this role, you will conduct computational biology for environmental surveillance applications, targeting diverse biologicals ranging from viruses to marine species. You will work with a team of biologists to build systems that integrate genomic surveillance capabilities to increase the speed and utility of genomics. You will apply traditional and state-of-the-art approaches to characterize complex microbial and eukaryotic communities and develop new methods to enable future capabilities.


As a Computational Biologist you will:


  • Conduct basic and applied research and development to analyze genomics data to characterize the genetic diversity of viruses, bacteria, and eukaryotic organisms.


  • Establish and maintain collaborative research with national and international laboratories to facilitate sustainable genomics research programs.


  • Support new concept development activities to expand the utility of operational genomics research across the APL enterprise.


  • Develop and maintain effective working relationships across the Department, Laboratory, and with external sponsors.

You meet our minimum qualifications for the job if you…


  • Have a Ph.D. in Bioinformatics, Biostatistics, Computational Biology, Computer Science, or other related fields with 1+ years of relevant experience or master’s degree with 4+ years of relevant experience.
  • Are proficient in one or more scripting languages, including shell scripting, R, and/or Python.
  • Have experience developing and executing customized, scalable, high-throughput sequencing pipelines.​​​​​​​​​​​​​​
  • Have experience working with publicly available sequencing datasets and/or public repositories for biological data, like SRA or NCBI.​​​​​​​
  • Have strong communication and collaboration skills, including the ability to lead and contribute to teams from any position.​​​​​​​
  • Are able to obtain a Secret level security clearance. If selected, you will be subject to a government security clearance investigation and must meet the requirements for access to classified information. Eligibility requirements include U.S. citizenship.​​​​​​​
  • Can demonstrate that you are fully vaccinated against COVID-19. To ensure the safety and well-being of the community, APL has established a policy requiring that all staff be vaccinated against COVID-19. All staff members must provide proof of full vaccination or have an approved medical or religious accommodation by their start date.


You'll go above and beyond our minimum requirements if you...


  • Have experience in application of AI/ML to biological systems data.​​​​​​​
  • Have experience using NGS data for one of the following: metagenomics analysis, phylogenetic analysis, disease surveillance.
  • Have experience analyzing second- and third-generation sequencing platform data, for example Illumina, Oxford Nanopore.
  • Have a background and publication history that includes work with environmental DNA and/or environmental metagenomics.
  • Have demonstrated success in obtaining funding from federal grant agencies.


Why work at APL?


The Johns Hopkins University Applied Physics Laboratory (APL) brings world-class expertise to our nation’s most critical defense, security, space and science challenges. While we are dedicated to solving complex challenges and pioneering new technologies, what makes us truly outstanding is our culture. We offer a vibrant, welcoming atmosphere where you can bring your authentic self to work, continue to grow, and build strong connections with inspiring teammates. 

At APL, we celebrate our differences and encourage creativity and bold, new ideas. Our employees enjoy generous benefits, including a robust education assistance program, unparalleled retirement contributions, and a healthy work/life balance. APL’s campus is located in the Baltimore-Washington metro area. Learn more about our career opportunities at www.jhuapl.edu/careers.

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